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	A novel poly (lactic-co-glycolic acid)-collagen hybrid scaffold fabricated via multi-nozzle low-temperature deposition
	Liu, Li ; Yan, Yongnian ; Xiong, Zhuo ; Zhang, Renji ; Wang, Xiaohong
	2010-05-10 ; 2010-05-10
会议名称	VIRTUAL AND RAPID MANUFACTURING - ADVANCED RESEARCH IN VIRTUAL AND RAPID PROTOTYPING ; 3rd International Conference on Advanced Research in Virtual and Rapid Prototyping ; Leiria, PORTUGAL ; Web of Science
关键词	COMPOSITE SCAFFOLD TISSUE STEREOLITHOGRAPHY CONSTRUCTS COPOLYMER IMPLANTS CELLS Engineering, Manufacturing Engineering, Civil Engineering, Electrical & Electronic Engineering, Mechanical
中文摘要	Scaffolds made from biodegradable materials play an important role in tissue engineering as a temporary support for cellular survival. An ideal scaffold for tissue engineering applications must demonstrate adequate strength and good properties to sustain cell adhesion, proliferation and differentiation. We constructed a PLGA-collagen hybrid scaffold with interconnected macro-channels via a Rapid Prototyping (RP) based Multi-nozzle Low-temperature Deposition and Manufacturing (M-LDM) system. Preliminary results show that the scaffold possesses interconnected micro-pores and macro-pores; the collagen sponge is strongly absorbed to PLGA matrices and a stable mesh is formed; the hybrid scaffold possesses stronger mechanical properties compared to collagen sponge and better hydrophilicity compared to PLGA scaffold; and this hybrid scaffold would be potentially used in bone and cartilage regeneration.
会议录出版者	TAYLOR & FRANCIS LTD ; LONDON ; 11 NEW FETTER LANE, LONDON EC4P 4EE, ENGLAND
语种	英语 ; 英语
内容类型	会议论文
源URL	[http://hdl.handle.net/123456789/19025]
专题	清华大学
推荐引用方式 GB/T 7714	Liu, Li,Yan, Yongnian,Xiong, Zhuo,et al. A novel poly (lactic-co-glycolic acid)-collagen hybrid scaffold fabricated via multi-nozzle low-temperature deposition[C]. 见:VIRTUAL AND RAPID MANUFACTURING - ADVANCED RESEARCH IN VIRTUAL AND RAPID PROTOTYPING, 3rd International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, PORTUGAL, Web of Science.

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