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	In vivo mechanical study of helical cardiac pacing electrode interacting with canine myocardium
	Zhang, Xiangming ; Ma, Nianke ; Fan, Hualin ; Niu, Guodong ; Yang, Wei
	2010-05-07 ; 2010-05-07
关键词	cardiac pacing helical electrode acute interactions myocardium Engineering, Mechanical Mechanics
中文摘要	Cardiac pacing is a medical device to help human to overcome arrhythmia and to recover the regular beats of heart. A helical configuration of electrode tip is a new type of cardiac pacing lead distal tip. The helical electrode attaches itself to the desired site of heart by screwing its helical tip into the myocardium. In vivo experiments on anesthetized dogs were carried out to measure the acute interactions between helical electrode and myocardium during screw-in and pull-out processes. These data would be helpful for electrode tip design and electrode/myocardium adherence safety evaluation. They also provide reliability data for clinical site choice of human heart to implant and to fix the pacing lead. A special design of the helical tip using strain gauges is instrumented for the measurement of the screw-in and pull-out forces. We obtained the data of screw-in torques and pull-out forces for five different types of helical electrodes at nine designed sites on ten canine hearts. The results indicate that the screw-in torques increased steplike while the torque-time curves presente saw-tooth fashion. The maximum torque has a range of 0.3-1.9 N mm. Obvious differences are observed for different types of helical tips and for different test sites. Large pull-out forces are frequently obtained at epicardium of left ventricle and right ventricle lateral wall, and the forces obtained at right ventricle apex and outflow tract of right ventricle are normally small. The differences in pull-out forces are dictated by the geometrical configuration of helix and regional structures of heart muscle.
语种	英语 ; 英语
出版者	SPRINGER HEIDELBERG ; HEIDELBERG ; TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/16202]
专题	清华大学
推荐引用方式 GB/T 7714	Zhang, Xiangming,Ma, Nianke,Fan, Hualin,et al. In vivo mechanical study of helical cardiac pacing electrode interacting with canine myocardium[J],2010, 2010.
APA	Zhang, Xiangming,Ma, Nianke,Fan, Hualin,Niu, Guodong,&Yang, Wei.(2010).In vivo mechanical study of helical cardiac pacing electrode interacting with canine myocardium..
MLA	Zhang, Xiangming,et al."In vivo mechanical study of helical cardiac pacing electrode interacting with canine myocardium".(2010).

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