QQ客服 官方微博 反馈留言

	MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue
	Ge, Guanglu ; Han, Dong ; Lin, Danying ; Chu, Weiguo ; Sun, Yunxu ; Jiang, Lei ; Ma, Wanyun ; Wang, Chen
	2010-05-06 ; 2010-05-06
关键词	atomic force microscopy magnetic AC mode astrocytes arterial intima field emission scanning electron microscopy VASCULAR STRUCTURE RECOGNITION PROTEINS RNA AFM DNA VISUALIZATION MORPHOLOGY ARTERIAL DYNAMICS Microscopy
中文摘要	Magnetic AC mode (MAC mode) atomic force microscopy (AFM), a novel type of tapping mode AFM in which the cantilever is driven directly by a magnetic field, is a powerful tool for imaging with high spatial resolution and better signal-to-noise in liquid environment. It may largely extend the application of AFM to living samples, especially those are sensitive to cantilever forces, even to multilayer tissue samples. However, there are few reports on the imaging of living cells by MAC mode AFM previously. In our present study, we explore the optimal imaging conditions of MAC mode AFM on living astrocytes and fresh arterial intima surface. We also used nude tips for PicoTREC panel (i.e., Aux in BNC, a new data collecting channel) to image living samples and discussed its difference with phase imaging. We show that living biological samples can be imaged by MAC mode AFM at details of comparable resolution as those by high resolution scanning electron microscopy. Furthermore, the combination of height, amplitude, phase and TREC panel signals provide abundant informations for the characteristics of living samples, such as topography, profile, stiffness and adhesion. (c) 2006 Elsevier B.V. All rights reserved.
语种	英语 ; 英语
出版者	ELSEVIER SCIENCE BV ; AMSTERDAM ; PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/14909]
专题	清华大学
推荐引用方式 GB/T 7714	Ge, Guanglu,Han, Dong,Lin, Danying,et al. MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue[J],2010, 2010.
APA	Ge, Guanglu.,Han, Dong.,Lin, Danying.,Chu, Weiguo.,Sun, Yunxu.,...&Wang, Chen.(2010).MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue..
MLA	Ge, Guanglu,et al."MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue".(2010).

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。