Ultralong hydroxyapatite microtubes: solvothermal synthesis and application in drug loading and sustained drug release

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 生物材料与组织工程研究中心 > 期刊论文

	Ultralong hydroxyapatite microtubes: solvothermal synthesis and application in drug loading and sustained drug release
	Zhang, Yong-Gang 1,2; Zhu, Ying-Jie 1,2; Chen, Feng 1; Sun, Tuan-Wei 1,2; Jiang, Ying-Ying 1,2
刊名	CRYSTENGCOMM
	2017-04-14
卷号	19 期号:14 页码:1965-1973
英文摘要	In this work, monodisperse single-crystalline ultralong hydroxyapatite (HAP) microtubes have been successfully synthesized using a reaction system containing CaCl2, NaOH, (NaPO3)(6), oleic acid, water and ethanol by a solvothermal method. The formation mechanism of HAP microtubes and the effects of solvothermal temperature, pH value, Ca/P molar ratio, and volume ratio of solvents on the product have been investigated. Due to the unique tubular structure, the as-prepared ultralong HAP microtubes exhibit high biocompatibility and superior properties in drug loading and sustained drug release. The as-prepared HAP microtubes are promising for applications in various biomedical fields such as drug/gene delivery and bone defect repair.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Multidisciplinary ; Crystallography
研究领域[WOS]	Chemistry ; Crystallography
关键词[WOS]	MICROWAVE-HYDROTHERMAL SYNTHESIS ; ORGANIC PHOSPHORUS SOURCE ; SINGLE-CRYSTAL GROWTH ; PROTEIN ADSORPTION ; CALCIUM-PHOSPHATE ; CARBON NANOTUBES ; NANOSTRUCTURED HYDROXYAPATITE ; BIOMEDICAL APPLICATIONS ; COMPOSITE SCAFFOLDS ; TEMPLATED SYNTHESIS
收录类别	SCI
语种	英语
WOS记录号	WOS:000398401800014
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/23760]
专题	上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文
作者单位	1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Yong-Gang,Zhu, Ying-Jie,Chen, Feng,et al. Ultralong hydroxyapatite microtubes: solvothermal synthesis and application in drug loading and sustained drug release[J]. CRYSTENGCOMM,2017,19(14):1965-1973.
APA	Zhang, Yong-Gang,Zhu, Ying-Jie,Chen, Feng,Sun, Tuan-Wei,&Jiang, Ying-Ying.(2017).Ultralong hydroxyapatite microtubes: solvothermal synthesis and application in drug loading and sustained drug release.CRYSTENGCOMM,19(14),1965-1973.
MLA	Zhang, Yong-Gang,et al."Ultralong hydroxyapatite microtubes: solvothermal synthesis and application in drug loading and sustained drug release".CRYSTENGCOMM 19.14(2017):1965-1973.