Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F
	Liang, Xiao 1,2; Zhang, Tian-Yuan 1,2; Zeng, Xue-Yi 1; Zheng, Yu 1,2; Wei, Kun 1; Yang, Yu-Rong1
刊名	JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
	2017-03-08
卷号	139 期号:9 页码:3364-3367
英文摘要	The first catalytic asymmetric total synthesis of the heptacyclic alkaloid (-)-communesin F is described. A key step features an iridium-catalyzed asymmetric intermolecular cascade cyclization, constructing the lower N,N-aminal-containing CDEF tetracyclic core in one step. Another notable element is the closure of final ring system (A ring) via a facile reduction of a twisted amide and concomitant cyclization activated by mesylation of N,O-hemiaminal intermediate.
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	ABSOLUTE STEREOCHEMICAL ASSIGNMENT ; ENANTIOSELECTIVE TOTAL-SYNTHESIS ; ALLYLIC ALKYLATION ; COMMUNESIN F ; QUATERNARY STEREOCENTERS ; 3-SUBSTITUTED INDOLES ; PENICILLIUM-EXPANSUM ; REVERSE PRENYLATION ; BIOMIMETIC APPROACH ; (+/-)-COMMUNESIN F
收录类别	SCI
语种	英语
WOS记录号	WOS:000396185700015
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/50996]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liang, Xiao,Zhang, Tian-Yuan,Zeng, Xue-Yi,et al. Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2017,139(9):3364-3367.
APA	Liang, Xiao,Zhang, Tian-Yuan,Zeng, Xue-Yi,Zheng, Yu,Wei, Kun,&Yang, Yu-Rong.(2017).Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,139(9),3364-3367.
MLA	Liang, Xiao,et al."Ir-Catalyzed Asymmetric Total Synthesis of (-)-Communesin F".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 139.9(2017):3364-3367.