Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 生物材料与组织工程研究中心 > 期刊论文

	Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment
	Sun, Tuan-Wei 1,2; Zhu, Ying-Jie 1,2; Chen, Feng 1; Zhang, Yong-Gang 1,2
刊名	CHEMISTRY-AN ASIAN JOURNAL
	2017-03-16
卷号	12 期号:6 页码:655-664
关键词	biomaterials biopaper collagen hydroxyapatite nanowires
英文摘要	Highly flexible hydroxyapatite/collagen (HAP/Col) composite membranes are regarded to be significant for guided bone regeneration application owing to their similar chemical composition to that of natural bone, excellent bioactivity and good osteoconductivity. However, the mechanical strength of the HAP/Col composite membranes is usually weak, which leads to difficult surgical operations and low mechanical stability during the bone healing process. Herein, highly flexible ultralong hydroxyapatite nanowires/collagen (UHANWs/Col) composite biopaper sheets with weight fractions of UHANWs ranging from 0 to 100% are facilely synthesized. The UHANWs are able to weave with each other to construct a three-dimensional fabric structure in the collagen matrix, providing a strong interaction between UHANWs and an intermolecular force between UHANWs and the collagen matrix. The as-prepared UHANWs/Col composite biopaper exhibits improved mechanical properties and high flexibility. More importantly, the as-prepared highly flexible 70wt% UHANWs/Col composite biopaper exhibits an excellent cytocompatibility and outstanding cellular attachment performance as compared with the pure collagen and 70wt% HAP nanorods/Col membranes. In consideration of its superior mechanical properties and outstanding cellular attachment performance, the as-prepared UHANWs/Col composite biopaper is promising for applications in various biomedical fields such as guided bone regeneration.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	GUIDED BONE REGENERATION ; POLYMER NANOCOMPOSITES ; SOLVOTHERMAL SYNTHESIS ; HYDROTHERMAL SYNTHESIS ; CREATINE-PHOSPHATE ; PROTEIN ADSORPTION ; COLLAGEN MEMBRANE ; PHOSPHORUS SOURCE ; DRUG-DELIVERY ; IN-VITRO
收录类别	SCI
语种	英语
WOS记录号	WOS:000398188600009
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/23691]
专题	上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文
作者单位	1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Sun, Tuan-Wei,Zhu, Ying-Jie,Chen, Feng,et al. Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment[J]. CHEMISTRY-AN ASIAN JOURNAL,2017,12(6):655-664.
APA	Sun, Tuan-Wei,Zhu, Ying-Jie,Chen, Feng,&Zhang, Yong-Gang.(2017).Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment.CHEMISTRY-AN ASIAN JOURNAL,12(6),655-664.
MLA	Sun, Tuan-Wei,et al."Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment".CHEMISTRY-AN ASIAN JOURNAL 12.6(2017):655-664.