| Racemic alkaloids from the fungus Ganoderma cochlear | |
Wang, Xin-Long1,2; Dou, Man2,3; Luo, Qi2 ; Cheng, Li-Zhi2,4; Yan, Yong-Ming2; Li, Rong-Tao3; Cheng, Yong-Xian1,2
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| 刊名 | FITOTERAPIA
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| 2017 | |
| 卷号 | 116期号:1页码:93-98 |
| 关键词 | Ganoderma cochlear Alkaloids ECD calculations Racemates Biosynthesis |
| 英文摘要 | Seven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting bodies of Ganoderma cochlear. The chemical structures of new compounds were elucidated on the basis of 1D and 2D NMR data. The absolute configurations of compounds 1,3-10 were assigned by ECD calculations. Biological activities of these isolates against renal fibrosis were accessed in rat normal or diseased renal interstitial fibroblast cells. Importantly, the plausible biosynthetic pathway for this class of alkaloids was originally proposed. (C) 2016 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | METABOLITES ; LUCIDUM ; MEROTERPENOIDS ; INHIBITORS ; POTENT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000392779200014 |
| 内容类型 | 期刊论文 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/45766]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Henan Univ Tradit Chinese Med, Zhengzhou 450008, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Kunming Univ Sci & Technol, Fac Life Sci & Engn, Kunming 650500, Peoples R China 4.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xin-Long,Dou, Man,Luo, Qi,et al. Racemic alkaloids from the fungus Ganoderma cochlear[J]. FITOTERAPIA,2017,116(1):93-98. |
| APA | Wang, Xin-Long.,Dou, Man.,Luo, Qi.,Cheng, Li-Zhi.,Yan, Yong-Ming.,...&Cheng, Yong-Xian.(2017).Racemic alkaloids from the fungus Ganoderma cochlear.FITOTERAPIA,116(1),93-98. |
| MLA | Wang, Xin-Long,et al."Racemic alkaloids from the fungus Ganoderma cochlear".FITOTERAPIA 116.1(2017):93-98. |
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