Strong Hydrophobic Interaction Between Graphene Oxide and Supported Lipid Bilayers Revealed by AFM

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	Strong Hydrophobic Interaction Between Graphene Oxide and Supported Lipid Bilayers Revealed by AFM
	Hu, XY; Lei, HZ; Zhang, XQ; Zhang, Y
刊名	MICROSCOPY RESEARCH AND TECHNIQUE
	2016
卷号	79 期号:8 页码:721-726
关键词	graphene oxide (GO) supported lipid bilayers (SLBs) hydrophobic interaction atomic force microscope (AFM)
ISSN号	1059-910X
通讯作者	Zhang, Y (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
英文摘要	Understanding the interaction between graphene oxide (GO) and lipid membranes is of great importance for its various applications in biotechnology. Here, we investigated the interaction between GO and charged supported lipid bilayers (SLBs) by in situ atomic force microscope (AFM) imaging. It was found that GO could peel off a single layer of positively charged SLBs and deposited on the hydrophobic part of the remaining sublayer. Then free lipid molecules would assemble on GO surface and formed 1.5 bilayers in a lipid-GO-lipid manner. For negatively charged lipid bilayers, however, GO deposited to the SLBs only when its concentration was very high. These results indicate that, in addition to electrostatic interaction, the hydrophobic interaction plays an important role when GO sheets deposit onto the charged lipid bilayers, and should be helpful to understand possible cytotoxicity and antibiosis of graphene-related nanomaterials. (C) 2016 Wiley Periodicals, Inc.
收录类别	SCI
语种	英语
WOS记录号	WOS:000380144800007
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/26632]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Hu, XY,Lei, HZ,Zhang, XQ,et al. Strong Hydrophobic Interaction Between Graphene Oxide and Supported Lipid Bilayers Revealed by AFM[J]. MICROSCOPY RESEARCH AND TECHNIQUE,2016,79(8):721-726.
APA	Hu, XY,Lei, HZ,Zhang, XQ,&Zhang, Y.(2016).Strong Hydrophobic Interaction Between Graphene Oxide and Supported Lipid Bilayers Revealed by AFM.MICROSCOPY RESEARCH AND TECHNIQUE,79(8),721-726.
MLA	Hu, XY,et al."Strong Hydrophobic Interaction Between Graphene Oxide and Supported Lipid Bilayers Revealed by AFM".MICROSCOPY RESEARCH AND TECHNIQUE 79.8(2016):721-726.