Lab on smartphone with interfaced electrochemical chips for on-site gender verification

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	Lab on smartphone with interfaced electrochemical chips for on-site gender verification
	Deng, WP; Dou, YZ; Song, P; Xu, H; Aldalbahi, A; Chen, N; El-Sayed, NN; Gao, JM; Lu, JX; Song, SP
刊名	JOURNAL OF ELECTROANALYTICAL CHEMISTRY
	2016
卷号	777 页码:117-122
关键词	On site detection Electrochemical Biosensor Gender verification Forensic
ISSN号	1572-6657
通讯作者	Zuo, XL (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China. ; Zuo, XL (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, Bioimaging Ctr, Shanghai 201800, Peoples R China. ; Gao, JM (reprint author), Wenzhou Med Univ, Sch Med Lab Sci & Life Sci, Wenzhou 325035, Peoples R China.
英文摘要	On-site detection of biomarkers in biofluids found at the crime scene is critically important forensic analysis. However, it remains difficult due to the lack of portable, fast and cheap on-site analytical devices. Traditional methods including polymerase chain reaction (PCR) and electrophoresis requires complicated instrumentation and critical environment. Optical analytical methods can be affected by intrinsic adsorption of complicated sample such as serum. In response, we developed a smartphone-interfaced electrochemical chip device for on-site gender verification. The detection is based on the known difference of biomarkers (creatine kinase (CR) and alanine transaminase (ALT)) between male and female groups. Enzyme cascade reaction converted the enzyme level in biofluids to the consumption of NADH, which can be electrochemically detected by our designed electrochemical chip. Our device retained the capability of gender verification when used in serum and serum stains. The detection can be completed in 20 min. Gender verification of real samples (39 serum samples) demonstrated excellent sensitivity and specificity of this smartphone based device. (C) 2016 Elsevier B.V. All rights reserved.
收录类别	SCI
语种	英语
WOS记录号	WOS:000383298100015
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/26556]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Deng, WP,Dou, YZ,Song, P,et al. Lab on smartphone with interfaced electrochemical chips for on-site gender verification[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY,2016,777:117-122.
APA	Deng, WP.,Dou, YZ.,Song, P.,Xu, H.,Aldalbahi, A.,...&Zuo, XL.(2016).Lab on smartphone with interfaced electrochemical chips for on-site gender verification.JOURNAL OF ELECTROANALYTICAL CHEMISTRY,777,117-122.
MLA	Deng, WP,et al."Lab on smartphone with interfaced electrochemical chips for on-site gender verification".JOURNAL OF ELECTROANALYTICAL CHEMISTRY 777(2016):117-122.