Enhanced osteogenic activity of poly ether ether ketone using calcium plasma immersion ion implantation | |
Lu, Tao; Qian, Shi; Meng, Fanhao; Ning, Congqin; Liu, Xuanyong | |
刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES |
2016-06-01 | |
卷号 | 142页码:192-198 |
关键词 | Plasma immersion ion implantation PEEK Calcium Osteogenic activity |
英文摘要 | As a promising implantable material, poly ether ether ketone (PEEK) possesses similar elastic modulus to that of cortical bones yet suffers from bio-inertness and poor osteogenic properties, which limits its application as orthopedic implants. In this work, calcium is introduced onto PEEK surface using calcium plasma immersion ion implantation (Ca-PIII). The results obtained from scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) confirm the modified layer with varying contents of calcium are formed on PEEK surfaces. Water contact angle measurements reveal the increasing hydrophobicity of both Ca-PIII treated surfaces. In vitro cell adhesion, viability assay, alkaline phosphatase activity and collagen secretion analyses disclose improved the adhesion, proliferation, and osteo-differentiation of rat bone mesenchymal stem cells (bMSCs) on Ca-PIII treated surfaces. The obtained results indicate that PEEK surface with enhanced osteogenic activity can be produced by calcium incorporation. (C) 2016 Elsevier B.V. All rights reserved. |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology |
类目[WOS] | Biophysics ; Chemistry, Physical ; Materials Science, Biomaterials |
研究领域[WOS] | Biophysics ; Chemistry ; Materials Science |
关键词[WOS] | IN-VITRO ; GENE-EXPRESSION ; STROMAL CELLS ; POLYETHERETHERKETONE ; TITANIUM ; SURFACE ; BONE ; BIOMATERIALS ; PROLIFERATION |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000375169600023 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/23061] |
专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
作者单位 | Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China |
推荐引用方式 GB/T 7714 | Lu, Tao,Qian, Shi,Meng, Fanhao,et al. Enhanced osteogenic activity of poly ether ether ketone using calcium plasma immersion ion implantation[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2016,142:192-198. |
APA | Lu, Tao,Qian, Shi,Meng, Fanhao,Ning, Congqin,&Liu, Xuanyong.(2016).Enhanced osteogenic activity of poly ether ether ketone using calcium plasma immersion ion implantation.COLLOIDS AND SURFACES B-BIOINTERFACES,142,192-198. |
MLA | Lu, Tao,et al."Enhanced osteogenic activity of poly ether ether ketone using calcium plasma immersion ion implantation".COLLOIDS AND SURFACES B-BIOINTERFACES 142(2016):192-198. |
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