Substantial enhancement of corrosion resistance and bioactivity of magnesium by incorporating calcium silicate particles | |
Huan, Zhiguang1; Xu, Chen1,2; Ma, Bing1; Zhou, Jie3; Chang, Jiang1 | |
刊名 | RSC ADVANCES |
2016 | |
卷号 | 6期号:53页码:47897-47906 |
英文摘要 | Biodegradable metal matrix composites (MMCs) with pure magnesium as the matrix and bioceramic calcium silicate (CS) as the reinforcement phase were fabricated by means of spark plasma sintering (SPS). The microstructure, mechanical properties and degradation behavior of the composites as well as the cellular responses to these composites were investigated. The formation of CS networks in the Mg matrix was observed when the CS content reached 20%. Among the composites with CS weight percentages ranging from 10% to 40%, the composite containing 20% CS possessed the highest structural compactness and compressive strength. Immersion tests in simulated body fluid (SBF) revealed that the Mg-20% CS composite exhibited a substantially enhanced corrosion resistance as compared with pure Mg, which was attributed to the formation of a hydroxyapatite (HA) layer on the surface as a result of the presence of the CS networks throughout the Mg matrix. In addition, ionic products from the interaction between the Mg-20% CS composite and SBF brought about a significant stimulatory effect on the alkaline phosphate (ALP) expression of MC3T3-E1 osteoblast cells. Our results indicate that CS is an effective reinforcement phase to improve both the corrosion resistance and bioactivity of Mg and the Mg-CS composites developed in this research are able to overcome the inherent drawbacks of magnesium as a biodegradable implant material. |
WOS标题词 | Science & Technology ; Physical Sciences |
类目[WOS] | Chemistry, Multidisciplinary |
研究领域[WOS] | Chemistry |
关键词[WOS] | METAL-MATRIX COMPOSITES ; SIMULATED BODY-FLUID ; IN-VITRO CORROSION ; BIOMEDICAL APPLICATIONS ; MECHANICAL-PROPERTIES ; STROMAL CELLS ; TRICALCIUM PHOSPHATE ; ALLOYS ; CERAMICS ; BEHAVIOR |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000377253400082 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/23001] |
专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, 319 Yueyang Rd, Shanghai 200050, Peoples R China 3.Delft Univ Technol, Dept Biomech Engn, Mekelweg 2, NL-2628 CD Delft, Netherlands |
推荐引用方式 GB/T 7714 | Huan, Zhiguang,Xu, Chen,Ma, Bing,et al. Substantial enhancement of corrosion resistance and bioactivity of magnesium by incorporating calcium silicate particles[J]. RSC ADVANCES,2016,6(53):47897-47906. |
APA | Huan, Zhiguang,Xu, Chen,Ma, Bing,Zhou, Jie,&Chang, Jiang.(2016).Substantial enhancement of corrosion resistance and bioactivity of magnesium by incorporating calcium silicate particles.RSC ADVANCES,6(53),47897-47906. |
MLA | Huan, Zhiguang,et al."Substantial enhancement of corrosion resistance and bioactivity of magnesium by incorporating calcium silicate particles".RSC ADVANCES 6.53(2016):47897-47906. |
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