Mesoporous Bioactive Glass Nanolayer-Modified Zirconia Coatings on Ti-6Al-4V with Improved In Vitro Bioactivity | |
Zhang, Yali1,2; Chen, Lei2; Shi, Mengchao2; Zhai, Dong2; Zhu, Huiying2; Chang, Jiang2; Wu, Chengtie2; Zheng, Xuebin3; Yin, Jingbo1 | |
刊名 | INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE |
2016-06-01 | |
卷号 | 7期号:2页码:216-228 |
关键词 | mesoporous bioactive glasses ZrO2 coatings bioactivity bone-forming activity |
英文摘要 | The bioactivity of coatings on alloy implants plays critical roles in the fast osteointegration and maintenance of a long-term life span of the implants. The aim of this study is to incorporate nanopores and bioactive components into the plasma-sprayed coatings by constructing nanopores and bioactive elements on the surface of coatings and further improve their in vitro bone-forming activity. In this study, mesoporous bioactive glasses (MBG) were used for modifying the surface of ZrO2 coatings on Ti-6Al-4V by spin-coating methods. The result shows that MBG nanolayer has been successfully coated on the surface of ZrO2 coatings. The MBG-modified ZrO2 coatings have improved apatite-mineralization ability and stable bonding strength. In addition, the attachment, proliferation, alkaline phosphate activity, and bone-related gene expression of rabbit bone marrow stromal cells on MBG-ZrO2 coating were also enhanced as compared with conventional bioactive glass-modified ZrO2 coatings and pure ZrO2 coatings. The results indicated that MBG-modified ZrO2 coatings on Ti alloy are promising for orthopedic application. |
WOS标题词 | Science & Technology ; Technology |
类目[WOS] | Materials Science, Ceramics |
研究领域[WOS] | Materials Science |
关键词[WOS] | OSTEOBLAST CELL-ADHESION ; OSTEOGENIC DIFFERENTIATION ; MEDICAL APPLICATIONS ; PROTEIN ADSORPTION ; BONE REGENERATION ; SILICA COATINGS ; STEM-CELLS ; SURFACE ; HYDROXYAPATITE ; ANGIOGENESIS |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000378724600012 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/22935] |
专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
作者单位 | 1.Shanghai Univ, Dept Polymer Mat, 333 Nanchen Rd, Shanghai 200444, Peoples R China 2.Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China 3.Chinese Acad Sci, Key Lab Inorgan Coating Mat, Shanghai Inst Ceram, Shanghai, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Yali,Chen, Lei,Shi, Mengchao,et al. Mesoporous Bioactive Glass Nanolayer-Modified Zirconia Coatings on Ti-6Al-4V with Improved In Vitro Bioactivity[J]. INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE,2016,7(2):216-228. |
APA | Zhang, Yali.,Chen, Lei.,Shi, Mengchao.,Zhai, Dong.,Zhu, Huiying.,...&Yin, Jingbo.(2016).Mesoporous Bioactive Glass Nanolayer-Modified Zirconia Coatings on Ti-6Al-4V with Improved In Vitro Bioactivity.INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE,7(2),216-228. |
MLA | Zhang, Yali,et al."Mesoporous Bioactive Glass Nanolayer-Modified Zirconia Coatings on Ti-6Al-4V with Improved In Vitro Bioactivity".INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE 7.2(2016):216-228. |
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