Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.
Zhu, Guo-Lei1,2; Nian, Yin1; Zhu, Di-Fan3; Wan, Luo-Sheng1,2; Bao, Ni-Man1,2; Wang, Wei-Hua1,2; Zhou, Lin1; Qiu, Ming-Hua1
刊名PHYTOCHEMISTRY LETTERS
2016-12-01
卷号18期号:1页码:105-112
关键词Cimicifuga foetida L. 9,19-Cycloartane triterpenoids Cytotoxicity
英文摘要Eight new cycloartane triterpenoids (1-8), along with eight known analogues (9-16), were isolated from the roots of Cimicifuga foetida L. Their structures were elucidated by spectroscopic analysis and acidic hydrolysis. All of the new compounds were evaluated for their in vitro cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480), and compound 2 showed inhibitory activities with IC50 values raging from 2.61 to 3.32 mu M. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
类目[WOS]Plant Sciences ; Oncology
研究领域[WOS]Plant Sciences ; Oncology
关键词[WOS]AERIAL PARTS ; CYCLOLANOSTANOL XYLOSIDES ; CYCLOARTANE TRITERPENOIDS ; GLYCOSIDES ; CONSTITUENTS ; RACEMOSA ; PROLIFERATION ; RHIZOME
收录类别SCI
语种英语
WOS记录号WOS:000389521800021
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/33781]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kuming 650500, Peoples R China
推荐引用方式
GB/T 7714
Zhu, Guo-Lei,Nian, Yin,Zhu, Di-Fan,et al. Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.[J]. PHYTOCHEMISTRY LETTERS,2016,18(1):105-112.
APA Zhu, Guo-Lei.,Nian, Yin.,Zhu, Di-Fan.,Wan, Luo-Sheng.,Bao, Ni-Man.,...&Qiu, Ming-Hua.(2016).Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L..PHYTOCHEMISTRY LETTERS,18(1),105-112.
MLA Zhu, Guo-Lei,et al."Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.".PHYTOCHEMISTRY LETTERS 18.1(2016):105-112.
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