The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye

CORC > 苏州纳米技术与纳米仿生研究所 > 中国科学院苏州纳米技术与纳米仿生研究所 > 纳米生物医学与安全研究部 > 裴仁军团队

	The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye
	Chen, X(陈星); Wang, J(王金娥); Jiang, GM(江桂梅); Zu, GY(祖广月); Liu, M(刘敏); Zhou, L(周璐); Pei, RJ(裴仁军)
刊名	RSC ADVANCES
	2016
卷号	6 期号:74
通讯作者	Pei, RJ(裴仁军)
英文摘要	A cyanine dye-dimethylindole red containing an extending polymethine chain, a sterically bulky dimethylindole heterocycle and an anionic propylsulfonate substituent on the quinoline ring was found to behave as a high specific light-up G-quadruplex probe in the red-emitting region above 650 nm, especially for parallel G-quadruplex c-myc. The 10 to 70-fold enhancement in the fluorescence quantum yield of dimethylindole red when incubating with G-quadruplexes may benefit more accurate definition of the distribution of G-quadruplexes across the genome.
关键词[WOS]	PARALLEL G-QUADRUPLEXES ; NAPHTHALENE DIIMIDE DYAD ; SWITCH-ON PROBE ; DISPLACEMENT ASSAY ; NUCLEIC-ACIDS ; DNA ; PROMOTER ; TRANSCRIPTION ; SELECTIVITY ; AFFINITY
收录类别	SCI ; EI
语种	英语
WOS记录号	WOS:000381512800057
内容类型	期刊论文
源URL	[http://ir.sinano.ac.cn/handle/332007/4911]
专题	苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_裴仁军团队
推荐引用方式 GB/T 7714	Chen, X,Wang, J,Jiang, GM,et al. The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye[J]. RSC ADVANCES,2016,6(74).
APA	Chen, X.,Wang, J.,Jiang, GM.,Zu, GY.,Liu, M.,...&Pei, RJ.(2016).The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye.RSC ADVANCES,6(74).
MLA	Chen, X,et al."The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye".RSC ADVANCES 6.74(2016).