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	Dextran Based Calcium Phosphate Nanoparticles for Dual-modal Imaging Guided Photothermal Therapy
	Peng Liu; Zexuan Ding; Huqiang Yi; Lintao Cai
	2015
会议名称	ChinaNanomedicine 2015
会议地点	Hangzhou, China
英文摘要	Photothermal therapy (PTT) is an appealing strategy for tumor treatment. To achieve high therapy efficiency, the location of tumor must be precisely identified before therapy. Dual-modal imaging guided photothermal therapy (PTT) is utlized as an effective treatment for tumor owing to its accurate imaging to tumor sites. Herein, we fabricated a dextran coated ICG/Gd3+ dual-doped calcium phosphate nanoparticle system. The obtained nanoparticles with an average diameter around 150 nm exhibit high ICG encapsulation efficiency (DLC: 10.9%) and good stability. Furthermore, it was proved that the obtained nanoparticles could serve as a contrast agent to NIR imaging and enhance MRI in vitro. In addition, the in vitro therapeutic examinations showed that this system was an effective agent for photothermal therapy of cancer.
收录类别	其他
语种	英语
WOS记录号	WOS:000373923400164
内容类型	会议论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/7444]
专题	深圳先进技术研究院_医药所
作者单位	2015
推荐引用方式 GB/T 7714	Peng Liu,Zexuan Ding,Huqiang Yi,et al. Dextran Based Calcium Phosphate Nanoparticles for Dual-modal Imaging Guided Photothermal Therapy[C]. 见:ChinaNanomedicine 2015. Hangzhou, China.

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