Antibacterial effects and biocompatibility of titanium surfaces with graded silver incorporation intitania nanotubes

	Antibacterial effects and biocompatibility of titanium surfaces with graded silver incorporation intitania nanotubes
	Mei, Shenglin; Wang, Huaiyu; Wang, Wei; Tong, Liping; Pan, Haobo; Ruan, Changshun; Ma, Qianli; Liu, Mengyuan; Yang, Huiling; Zhang, Liang
刊名	BIOMATERIALS
	2014
英文摘要	Most commercial dental implants are made of titanium (Ti) because Ti possesses excellent properties such as osseointegration. However, many types of Ti products still suffer from insufficient antibacterial capability and bacterial infection after surgery remains one of the most common and intractable complications. In this study, a dual process encompassing anodization and silver plasma immersion ion implantation (Ag PIII) is utilized to produce titaniananotubes (TiO2-NTs) containing Ag at different sites and depths. The concentration and depth of the incorporated Ag can be tailored readily by changing the PIII parameters. The Ag-embedded TiO2-NTs which retain the nanotubular morphology are capable of sterilizing oral pathogens as opposed to pure Ti plates and pristine TiO2-NTs. Biological assays indicate that the in vitro and in vivo biocompatibility of the sample plasma-implanted at a lower voltage of 0.5 kV (NT-Ag-0.5) is significantly compromised due to the large amount of surface Ag. On the other hand, the sample implanted at 1 kV (NT-Ag-1.0) exhibits unimpairedeffects due to the smaller surface Ag accumulation. Sample NT-Ag-1.0 is further demonstrated to possess sustained antibacterial properties due to the large embedded depth of Ag and the technique and resulting materials have large potential in dental implants. (C) 2014 Elsevier Ltd. All rights reserved.
收录类别	SCI
原文出处	http://www.sciencedirect.com/science/article/pii/S0142961214001318
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/6094]
专题	深圳先进技术研究院_医药所
作者单位	BIOMATERIALS
推荐引用方式 GB/T 7714	Mei, Shenglin,Wang, Huaiyu,Wang, Wei,et al. Antibacterial effects and biocompatibility of titanium surfaces with graded silver incorporation intitania nanotubes[J]. BIOMATERIALS,2014.
APA	Mei, Shenglin.,Wang, Huaiyu.,Wang, Wei.,Tong, Liping.,Pan, Haobo.,...&Chu, Paul K..(2014).Antibacterial effects and biocompatibility of titanium surfaces with graded silver incorporation intitania nanotubes.BIOMATERIALS.
MLA	Mei, Shenglin,et al."Antibacterial effects and biocompatibility of titanium surfaces with graded silver incorporation intitania nanotubes".BIOMATERIALS (2014).