Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized

	Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized
	Jiang, Zhiwu; Deng, Manman; Wei, Xinru; Ye, Wei; Xiao, Yiren; Lin, Simiao; Wang, Suna; Li, Baiheng; Liu, Xin; Zhang, Gong
刊名	JOURNAL OF HEMATOLOGY & ONCOLOGY
	2016
英文摘要	The existence and identification of leukemia-initiating cells in adult acute B lymphoblastic leukemia (B-ALL) remain controversial. We examined whether adult B-ALL is hierarchically organized into phenotypically distinct subpopulations of leukemogenic and non-leukemogenic cells or whether most B-ALL cells retain leukemogenic capacity, irrespective of their immunophenotype profiles. Our results suggest that adult B-ALL follows the stochastic stem cell model and that the expression of CD34 and CD38 in B-ALL is reversibly and not hierarchically organized.
收录类别	SCI
原文出处	http://download.springer.com/static/pdf/989/art%253A10.1186%252Fs13045-016-0310-1.pdf?originUrl=http%3A%2F%2Fjhoonline.biomedcentral.com%2Farticle%2F10.1186%2Fs13045-016-0310-1&token2=exp=1476694849~acl=%2Fstatic%2Fpdf%2F989%2Fart%25253A10.1186%25252Fs13045-016-0310-1.pdf*~hmac=aa12c61ae9623e5f1104b278b0051335cafd128f0bc232bee1178e2320a651bd
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/10475]
专题	深圳先进技术研究院_医工所
作者单位	JOURNAL OF HEMATOLOGY & ONCOLOGY
推荐引用方式 GB/T 7714	Jiang, Zhiwu,Deng, Manman,Wei, Xinru,et al. Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized[J]. JOURNAL OF HEMATOLOGY & ONCOLOGY,2016.
APA	Jiang, Zhiwu.,Deng, Manman.,Wei, Xinru.,Ye, Wei.,Xiao, Yiren.,...&Li, Peng.(2016).Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized.JOURNAL OF HEMATOLOGY & ONCOLOGY.
MLA	Jiang, Zhiwu,et al."Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized".JOURNAL OF HEMATOLOGY & ONCOLOGY (2016).