Y-chromosome evidence of southern origin of the East Asian - Specific haplogroup O3-M122

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	Y-chromosome evidence of southern origin of the East Asian - Specific haplogroup O3-M122
	Shi H 1,2,6; Dong YL 3; Wen B 4; Xiao CJ 3; Underhill PA 5; Shen PD 5; Chakraborty R 7; Jin L 4,7; Su B[*]1,2,7
刊名	AMERICAN JOURNAL OF HUMAN GENETICS
	2005
卷号	77 期号:3 页码:408-419
ISSN号	0002-9297
通讯作者	sub@mail.kiz.ac.cn
合作状况	其它
英文摘要	The prehistoric peopling of East Asia by modern humans remains controversial with respect to early population migrations. Here, we present a systematic sampling and genetic screening of an East Asian-specific Y-chromosome haplogroup (O3-M122) in 2,332 individuals from diverse East Asian populations. Our results indicate that the O3-M122 lineage is dominant in East Asian populations, with an average frequency of 44.3%. The microsatellite data show that the O3-M122 haplotypes in southern East Asia are more diverse than those in northern East Asia, suggesting a southern origin of the O3-M122 mutation. It was estimated that the early northward migration of the O3-M122 lineages in East Asia occurred similar to 25,000-30,000 years ago, consistent with the fossil records of modern humans in East Asia.
收录类别	SCI
资助信息	This study was supported by grantsfromtheChinese Academy of Sciences (KSCX2-SW-121), the National Natural Science Foundation of China (30370755 and 30440018), the Natural Science Foundation of Yunnan Province of China, and the National 973 Project of China (2006CB701506).
原文出处	200577408.pdf
语种	英语
公开日期	2010-08-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/2131]
专题	昆明动物研究所_比较基因组学昆明动物研究所_中国科学院昆明灵长类研究中心昆明动物研究所_细胞与分子进化重点实验室
作者单位	1.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology 2.Chinese Acad Sci, Kunming Primate Res Ctr, Kunming, Peoples R China 3.Key Laboratory of Bio-resources Conservation and Utilization and Human Genetics Center, Yunnan University, Kunming, China 4.State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai 5.Department of Genetics, Stanford University, Stanford, CA 6.Graduate School of Chinese Academy of Science, Beijing 7.Center for Genome Information, University of Cincinnati, Cincinnati
推荐引用方式 GB/T 7714	Shi H,Dong YL,Wen B,et al. Y-chromosome evidence of southern origin of the East Asian - Specific haplogroup O3-M122[J]. AMERICAN JOURNAL OF HUMAN GENETICS,2005,77(3):408-419.
APA	Shi H.,Dong YL.,Wen B.,Xiao CJ.,Underhill PA.,...&Su B[*].(2005).Y-chromosome evidence of southern origin of the East Asian - Specific haplogroup O3-M122.AMERICAN JOURNAL OF HUMAN GENETICS,77(3),408-419.
MLA	Shi H,et al."Y-chromosome evidence of southern origin of the East Asian - Specific haplogroup O3-M122".AMERICAN JOURNAL OF HUMAN GENETICS 77.3(2005):408-419.