Highly Diastereo- and Enantioselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Aziridines and alpha,beta-Unsaturated Ketones

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	Highly Diastereo- and Enantioselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Aziridines and alpha,beta-Unsaturated Ketones
	Xu CF(许超凡)1; Zheng BH(郑宝会)1; Suo JJ(索嘉嘉)1; Ding CH(丁昌华)1; Hou XL(侯雪龙)1
刊名	Angew. Chem.-Int. Edit.
	2015
卷号	54 期号:5 页码:1604-1607
其他题名	烯基氮杂环丙烷和a,b-不饱和酮的钯催化高非对映选择性, 高对映选择性[3+2]环加成反应
通讯作者	丁昌华 ; 侯雪龙
英文摘要	A palladium-catalyzed asymmetric [3+2] cycloaddition reaction of vinylaziridines with alpha,beta-unsaturated ketones, wherein the alkenes have a single activator, is realized in high diastereo- and enantioselectivity, thus affording 3,4-disubstituted pyrrolidines in high yields with excellent ee values. The introduction of a methyl group at C1 of the vinyl group the vinylaziridines greatly improves the stereochemistry of the reaction. A plausible transition state is proposed.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/anie.201409467
语种	英语
WOS记录号	WOS:000348713900038
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/39566]
专题	上海有机化学研究所_金属有机化学国家重点实验室
作者单位	1.中科院上海有机化学研究所, 金属有机化学国家重点实验室 2.中科院上海有机化学研究所, 沪港合成化学联合实验室
推荐引用方式 GB/T 7714	Xu CF,Zheng BH,Suo JJ,et al. Highly Diastereo- and Enantioselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Aziridines and alpha,beta-Unsaturated Ketones[J]. Angew. Chem.-Int. Edit.,2015,54(5):1604-1607.
APA	许超凡,郑宝会,索嘉嘉,丁昌华,&侯雪龙.(2015).Highly Diastereo- and Enantioselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Aziridines and alpha,beta-Unsaturated Ketones.Angew. Chem.-Int. Edit.,54(5),1604-1607.
MLA	许超凡,et al."Highly Diastereo- and Enantioselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Aziridines and alpha,beta-Unsaturated Ketones".Angew. Chem.-Int. Edit. 54.5(2015):1604-1607.