Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars

	Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
	Qian, Bao-Chen 1,5; Kamori, Akiko 2; Kinami, Kyoko 2; Kato, Atsushi 2; Li, Yi-Xian 1; Fleet, George W. J.3,4; Yu, Chu-Yi 1,4
刊名	ORGANIC & BIOMOLECULAR CHEMISTRY
	2016
卷号	14 期号:19 页码:4488-4498
英文摘要	Epimerization of C5 of an N-hydroxypyrrolidine ring by regioselective oxidation to a nitrone followed by diastereoselective reduction provides a new approach to the synthesis of swainsonine and related compounds. The only protection in the synthesis of the potent mannosidase inhibitor DIM (1,4-dideoxy-1,4-imino-D-mannitol) was the acetonation of D-mannose.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/36130]
专题	化学研究所_分子识别与功能实验室
作者单位	1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China 2.Toyama Univ, Dept Hosp Pharm, 2630 Sugitani, Toyama 9300194, Japan 3.Univ Oxford, Dept Chem, Chem Res Lab, Mansfield Rd, Oxford OX1 3TA, England 4.Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Qian, Bao-Chen,Kamori, Akiko,Kinami, Kyoko,et al. Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2016,14(19):4488-4498.
APA	Qian, Bao-Chen.,Kamori, Akiko.,Kinami, Kyoko.,Kato, Atsushi.,Li, Yi-Xian.,...&Yu, Chu-Yi.(2016).Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars.ORGANIC & BIOMOLECULAR CHEMISTRY,14(19),4488-4498.
MLA	Qian, Bao-Chen,et al."Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars".ORGANIC & BIOMOLECULAR CHEMISTRY 14.19(2016):4488-4498.