Super-resolution imaging and tracking of TGF-beta receptor II on living cells

CORC > 化学研究所 > 中国科学院化学研究所 > 分子纳米结构与纳米技术实验室

	Super-resolution imaging and tracking of TGF-beta receptor II on living cells
	Ye, Zi; Li, Nan; Zhao, Libo; Sun, Yahong; Ruan, Hefei; Zhang, Mingliang; Yuan, Jinghe; Fang, Xiaohong
刊名	SCIENCE BULLETIN
	2016-04-01
卷号	61 期号:8 页码:632-638
关键词	Single-particle tracking Photoactivated localization microscopy Single-molecule fluorescence imaging TGF-beta receptor II Membrane diffusion
英文摘要	Single-particle tracking photoactivated localization microscopy (sptPALM) has recently emerged as a powerful tool for high-density imaging and tracking of individual molecules in living cells. In this work, we have monitored and compared the diffusion dynamics of TGF-beta type II receptor (T beta RII) at high expression level using both traditional single-particle tracking (SPT) and sptPALM. The ligand-induced aggregation of TbRII oligomers was further indicated by sptPALM. Due to the capacity of distinguishing and tracking single molecules within diffraction limit, sptPALM outperforms traditional SPT by providing more accurate biophysical information.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/36033]
专题	化学研究所_分子纳米结构与纳米技术实验室
作者单位	Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Ye, Zi,Li, Nan,Zhao, Libo,et al. Super-resolution imaging and tracking of TGF-beta receptor II on living cells[J]. SCIENCE BULLETIN,2016,61(8):632-638.
APA	Ye, Zi.,Li, Nan.,Zhao, Libo.,Sun, Yahong.,Ruan, Hefei.,...&Fang, Xiaohong.(2016).Super-resolution imaging and tracking of TGF-beta receptor II on living cells.SCIENCE BULLETIN,61(8),632-638.
MLA	Ye, Zi,et al."Super-resolution imaging and tracking of TGF-beta receptor II on living cells".SCIENCE BULLETIN 61.8(2016):632-638.