Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology

	Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology
	Wu, Hongliang 1,2,3; Li, Guoliang 1; Liu, Shucheng 4; Hu, Na 2,3; Geng, Dandan 2,3; Chen, Guang 1; Sun, Zhiwei 1; Zhao, Xianen 1; Xia, Lian 1; You, Jinmao 1,2
刊名	food chemistry
	2016-02-01
卷号	192 页码:98-106
关键词	Endocrine disrupting chemicals Dispersive liquid-liquid microextraction Pre-column derivatization High-performance liquid chromatography with fluorescence detection Box-Behnken design
英文摘要	this research established a sensitive and efficient pre-column derivatization hplc method based on dispersive liquid-liquid microextraction (dllme) for the simultaneous determination of six steroidal and phenolic endocrine disrupting chemicals (edcs). in this study, edcs were firstly labeled by the derivatization reagent 2-(11h-benzo[a]carbazol-11-yl) ethyl carbonochloridate (bcec-cl) and then extracted by dllme. the response surface methodology was employed to investigate the key parameters of pre-column derivatization and dllme. under the optimal conditions, a good linear relationship between the peak area and the concentration of analytes was observed with correlation coefficients of >0.9991. limits of detection for all edcs derivatives were achieved within the range of 0.02-0.07 mu g l-1. the proposed method has the advantages of simple operation, low consumption of organic solvent, saving time, low output limit and good selectivity. when applied to several food and water samples analysis, it demonstrated good applicability for the determination of edcs. (c) 2015 elsevier ltd. all rights reserved.
WOS标题词	science & technology ; physical sciences ; life sciences & biomedicine
类目[WOS]	chemistry, applied ; food science & technology ; nutrition & dietetics
研究领域[WOS]	chemistry ; food science & technology ; nutrition & dietetics
关键词[WOS]	tandem mass-spectrometry ; solid-phase extraction ; cloud-point extraction ; gas-chromatography ; estrogenic compounds ; bisphenol-a ; human urine ; hplc ; preconcentration ; optimization
收录类别	SCI
语种	英语
WOS记录号	WOS:000362304500013
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6527]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Qufu Normal Univ, Key Lab Life Organ Anal Shandong Prov, Qufu, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Peoples R China 3.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China 4.Guangdong Ocean Univ, Coll Food Sci & Technol, Guangdong Prov Key Lab Aquat Prod Proc & Safety, Zhanjiang, Peoples R China
推荐引用方式 GB/T 7714	Wu, Hongliang,Li, Guoliang,Liu, Shucheng,et al. Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology[J]. food chemistry,2016,192:98-106.
APA	Wu, Hongliang.,Li, Guoliang.,Liu, Shucheng.,Hu, Na.,Geng, Dandan.,...&You, Jinmao.(2016).Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology.food chemistry,192,98-106.
MLA	Wu, Hongliang,et al."Monitoring the contents of six steroidal and phenolic endocrine disrupting chemicals in chicken, fish and aquaculture pond water samples using pre-column derivatization and dispersive liquid-liquid microextraction with the aid of experimental design methodology".food chemistry 192(2016):98-106.