Eight linear peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020 | |
Liang, Xiao; Zhang, Xiao-Yong; Nong, Xu-Hua; Wang, Jie; Huang, Zhong-Hui; Qi, Shu-Hua | |
刊名 | TETRAHEDRON |
2016 | |
卷号 | 72期号:22页码:3092-3097 |
关键词 | Deep-sea-derived fungus Simplicillium obclavatum Linear peptide Antifouling Cytotoxicity |
通讯作者 | Qi, SH (reprint author), Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China. |
中文摘要 | Eight new linear peptides, simplicilliumtides A-H (1-8) were isolated from a culture broth of the deep-sea-derived fungal strain Simplicillium obclavatum EIODSF 020. Their structures were elucidated by spectroscopic analysis, and their absolute configurations were determined by Marfey's method. Compounds 1-2 are linear tetrapeptides possessing a 2-aminobenzoic acid residue. Compounds 3-8 are acetylated linear tri- or di-peptides. Their antifouling, antibacterial, cytotoxic, and acetylcholinesterase inhibiting activities were evaluated. Compound 4 showed strong antifouling activity against Bugula neritina larvae settlement. And 1, 5, 7 and 8 showed weak cytotoxicity towards human leukemia HL-60 or K562 cell line. (C) 2016 Elsevier Ltd. All rights reserved. |
学科主题 | Chemistry |
内容类型 | 期刊论文 |
源URL | [http://ir.scsio.ac.cn/handle/344004/15397] |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
推荐引用方式 GB/T 7714 | Liang, Xiao,Zhang, Xiao-Yong,Nong, Xu-Hua,et al. Eight linear peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020[J]. TETRAHEDRON,2016,72(22):3092-3097. |
APA | Liang, Xiao,Zhang, Xiao-Yong,Nong, Xu-Hua,Wang, Jie,Huang, Zhong-Hui,&Qi, Shu-Hua.(2016).Eight linear peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020.TETRAHEDRON,72(22),3092-3097. |
MLA | Liang, Xiao,et al."Eight linear peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020".TETRAHEDRON 72.22(2016):3092-3097. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论