Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging

CORC > 上海光学精密机械研究所 > 中国科学院上海光学精密机械研究所 > 信息光学与光电技术实验室

	Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging
	Zhu, Jing ; Gong, Tianxun ; Kopwitthaya, Atcha ; Hu, Rui ; Law, Wing-Cheung ; Roy, Indrajit ; Huang, Huijie ; Yong, Ken-Tye
刊名	rsc adv.
	2013
卷号	3 期号:30 页码:12280
通讯作者	huang, hj (reprint author), shanghai inst opt & fine mech, chinese acad sci, shanghai 201800, peoples r china.
英文摘要	in this contribution, we show that au nrs functionalized with peg molecules can be used as absorption nanoprobes for near-infrared imaging in live animals. we have found that the contrast signal of the in vivo image is dependent upon the transmission ability of the nir light interacting with the different aspect ratios of au nrs. our study was focused on absorption in vivo imaging at 700 nm, which is within the transmission window of the skin. nir absorption in vivo imaging was carried out by subcutaneous injection of mice with pegylated au nrs that have a lspr around 700 nm. the formulation showed strong contrast signals under the tissues upon irradiation with nir light. more importantly, our theoretical calculation suggested that the high contrast signals from the pegylated au nrs were generated via the nir light absorption of the au nrs within the tissue.
收录类别	SCI
语种	英语
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.siom.ac.cn/handle/181231/14829]
专题	上海光学精密机械研究所_信息光学与光电技术实验室
作者单位	1.[Zhu, Jing 2.Huang, Huijie] Shanghai Inst Opt & Fine Mech, Chinese Acad Sci, Shanghai 201800, Peoples R China 3.[Gong, Tianxun 4.Hu, Rui 5.Yong, Ken-Tye] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore 6.[Kopwitthaya, Atcha 7.Law, Wing-Cheung] SUNY Buffalo, ILPB, Buffalo, NY 14260 USA 8.[Roy, Indrajit] Univ Delhi, Dept Chem, Delhi 110007, India 9.[Law, Wing-Cheung] Hong Kong Polytech Univ, Dept Ind & Syst Engn, Kowloon, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Jing,Gong, Tianxun,Kopwitthaya, Atcha,et al. Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging[J]. rsc adv.,2013,3(30):12280.
APA	Zhu, Jing.,Gong, Tianxun.,Kopwitthaya, Atcha.,Hu, Rui.,Law, Wing-Cheung.,...&Yong, Ken-Tye.(2013).Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging.rsc adv.,3(30),12280.
MLA	Zhu, Jing,et al."Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging".rsc adv. 3.30(2013):12280.