Efficient fermentative production of polymer-grade D-lactate by an engineered alkaliphilic Bacillus sp strain under non-sterile conditions
Assavasirijinda, Nilnate1,3; Ge, Deyong1; Yu, Bo2; Xue, Yanfen1; Ma, Yanhe1,4
刊名MICROBIAL CELL FACTORIES
2016-01-12
卷号15期号:3
关键词Alkaliphilic Bacillus sp. D-lactate Non-sterile fermentation Peanut meal
英文摘要Background: Polylactic acid (PLA) is one important chemical building block that is well known as a biodegradable and a biocompatible plastic. The traditional lactate fermentation processes need CaCO3 as neutralizer to maintain the desired pH, which results in an amount of insoluble CaSO4 waste during the purification process. To overcome such environmental issue, alkaliphilic organisms have the great potential to be used as an organic acid producer under NaOH-neutralizing agent based fermentation. Additionally, high optical purity property in D-lactic acid is now attracting more attention from both scientific and industrial communities because it can improve mechanical properties of PLA by blending l-or D-polymer together. However, the use of low-price nitrogen source for D-lactate fermentation by alkaliphilic organisms combined with NaOH-neutralizing agent based process has not been studied. Therefore, our goal was the demonstrations of newly simplify high-optical-purity D-lactate production by using low-priced peanut meal combined with non-sterile NaOH-neutralizing agent based fermentation.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biotechnology & Applied Microbiology
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]HIGH-OPTICAL-PURITY ; L-LACTIC ACID ; ESCHERICHIA-COLI ; SUBTILIS
收录类别SCI
语种英语
WOS记录号WOS:000368123500001
内容类型期刊论文
源URL[http://124.16.173.210/handle/834782/1547]  
专题天津工业生物技术研究所_酶工程实验室 马延和 _期刊论文
作者单位1.Chinese Acad Sci, Inst Microbiol, State Key Lab Microbial Resources, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, CAS Key Lab Microbial Physiol & Metab Engn, Beijing 100101, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China
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Assavasirijinda, Nilnate,Ge, Deyong,Yu, Bo,et al. Efficient fermentative production of polymer-grade D-lactate by an engineered alkaliphilic Bacillus sp strain under non-sterile conditions[J]. MICROBIAL CELL FACTORIES,2016,15(3).
APA Assavasirijinda, Nilnate,Ge, Deyong,Yu, Bo,Xue, Yanfen,&Ma, Yanhe.(2016).Efficient fermentative production of polymer-grade D-lactate by an engineered alkaliphilic Bacillus sp strain under non-sterile conditions.MICROBIAL CELL FACTORIES,15(3).
MLA Assavasirijinda, Nilnate,et al."Efficient fermentative production of polymer-grade D-lactate by an engineered alkaliphilic Bacillus sp strain under non-sterile conditions".MICROBIAL CELL FACTORIES 15.3(2016).
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