A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 环境资源化与水回用团队

	A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide
	Lang, Qiaolin 1,2,3; Han, Lei 1,2,3; Hou, Chuantao 1,2; Wang, Fei 1,2; Liu, Aihua 1,2
刊名	TALANTA
	2016-08-15
卷号	156 页码:34-41
关键词	Acetylcholinesterase biosensor Gold nanorods Au@Ag heterogeneous NRs Organophosphate pesticide
英文摘要	A sensitive amperometric acetylcholinesterase (AChE) biosensor, based on gold nanorods (AuNRs), was developed for the detection of organophosphate pesticide. Compared with Au@Ag heterogeneous NRs, AuNRs exhibited excellent electrocatalytic properties, which can electrocatalytically oxidize thiocholine, the hydrolysate of acetylthiocholine chloride (ATCI) by AChE at +0.55 V (vs. SCE). The AChE/AuNRs/GCE biosensor was fabricated on basis of the inhibition of AChE activity by organophosphate pesticide. The biosensor could detect paraoxon in the linear range from 1 nM to 5 mu M and dimethoate in the linear range from 5 nM to 1 mu M, respectively. The detection limits of paraoxon and dimethoate were 0.7 nM and 3.9 nM, which were lower than the reported AChE biosensor. The proposed biosensor could restore to over 95% of its original current, which demonstrated the good reactivation. Moreover, the biosensor can be applicable to real water sample measurement. Thus, the biosensor exhibited low applied potential, high sensitivity and good stability, providing a promising tool for analysis of pesticides. (C) 2016 Elsevier B.V. All rights reserved.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Analytical
研究领域[WOS]	Chemistry
关键词[WOS]	AG HETEROGENEOUS NANORODS ; GLUCOSE-OXIDASE ; MICROBIAL BIOSENSOR ; MULTIRESIDUE METHOD ; CARBON NANOTUBES ; NERVE AGENTS ; NANOPARTICLES ; SURFACE ; SENSOR ; HYDROLASE
收录类别	SCI
语种	英语
WOS记录号	WOS:000378182900006
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/8336]
专题	青岛生物能源与过程研究所_环境资源化与水回用团队
作者单位	1.Qingdao Univ, Inst Biosensing, Qingdao 266071, Peoples R China 2.Qingdao Univ, Coll Chem & Chem Engn, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Lab Biosensing, 189 Songling Rd, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Lang, Qiaolin,Han, Lei,Hou, Chuantao,et al. A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide[J]. TALANTA,2016,156:34-41.
APA	Lang, Qiaolin,Han, Lei,Hou, Chuantao,Wang, Fei,&Liu, Aihua.(2016).A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide.TALANTA,156,34-41.
MLA	Lang, Qiaolin,et al."A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide".TALANTA 156(2016):34-41.