The Mechanical Analysis of the Biofilm Streamer Nucleation and Geometry Characterization in Microfluidic Channels

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	The Mechanical Analysis of the Biofilm Streamer Nucleation and Geometry Characterization in Microfluidic Channels
	Wang XL; Hao MD; Du X; Wang GQ; Matsushita J
刊名	COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
	2016
通讯作者邮箱	xiaoling@me.ustb.edu.cn
页码	7819403
关键词	Gradient structure Strain hardening Ductility Transformation-induced plasticity Strain partitioning
ISSN号	1748-670X
通讯作者	Wang, XL (reprint author), Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China. ; Wang, XL (reprint author), Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA. ; Wang, XL (reprint author), Chinese Acad Sci, Inst Mech, Lab Nonlinear Mech, Beijing 100190, Peoples R China.
产权排序	[Wang, Xiaoling; Hao, Mudong; Du, Xin; Wang, Guoqing] Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China; [Wang, Xiaoling] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA; [Wang, Xiaoling] Chinese Acad Sci, Inst Mech, Lab Nonlinear Mech, Beijing 100190, Peoples R China; [Matsushita, Jun-ichi] Tokai Univ, Dept Mat Sci, Hiratsuka, Kanagawa 2591292, Japan
中文摘要	Bacteria can form biofilm streamers in microfluidic channels with various geometries. Experiments show that the streamer geometry, such as its shape or thickness, depends on the fluid velocity and the geometry and curvature of the microfluidic channel. In the paper, a mechanical analysis of the flow field is made in different channels, which shows that the secondary flow in the channel is the reason for streamer nucleation and that the shear stress distribution decides the streamer geometry including shape and thickness. Through a finite elements simulation, we obtain the secondary flow forming positions in both static and rotating channels: positions that are the location of nucleation of the streamer. Thick or wide biofilm streamers occur at the points of minimum shear stress in static channels. Furthermore, in rotating channels, spiral-like streamers form, due to the helical shape of the minimum shear stress distribution. The findings may allow the prevention of biofilm formation and also the removal of bacteria adhered onto certain surfaces in channels with small cross sections. The analysis also indicates how one can obtain desirable biofilm streamers by control of the channel geometry and the loading conditions.
分类号	Q4
类目[WOS]	Mathematical & Computational Biology
研究领域[WOS]	Mathematical & Computational Biology
关键词[WOS]	Gradient structure ; Strain hardening ; Ductility ; Transformation-induced plasticity ; Strain partitioning
收录类别	SCI
原文出处	http://dx.doi.org/10.1155/2016/7819403
语种	英语
WOS记录号	WOS:000377886400001
内容类型	期刊论文
源URL	[http://dspace.imech.ac.cn/handle/311007/59527]
专题	力学研究所_非线性力学国家重点实验室
推荐引用方式 GB/T 7714	Wang XL,Hao MD,Du X,et al. The Mechanical Analysis of the Biofilm Streamer Nucleation and Geometry Characterization in Microfluidic Channels[J]. COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE,2016:7819403.
APA	Wang XL,Hao MD,Du X,Wang GQ,&Matsushita J.(2016).The Mechanical Analysis of the Biofilm Streamer Nucleation and Geometry Characterization in Microfluidic Channels.COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE,7819403.
MLA	Wang XL,et al."The Mechanical Analysis of the Biofilm Streamer Nucleation and Geometry Characterization in Microfluidic Channels".COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2016):7819403.