Study on mercury-binding proteins in rats by hyphenated technique of high performance liquid chromatography-isotope dilution-inductively coupled plasma-mass Spectrometry

	Study on mercury-binding proteins in rats by hyphenated technique of high performance liquid chromatography-isotope dilution-inductively coupled plasma-mass Spectrometry
	Shi JW(史俊稳); Feng WY(丰伟悦); Wang M(王萌); Li B(李柏); Wang B(汪冰); Zhu MT(朱墨桃); Chai ZF(柴之芳); Shi, JW; Feng, WY; Meng, W
刊名	CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
	2007
卷号	35 期号:6 页码:803-808
关键词	high performance liquid chromatography isotope dilution inductively coupled plasma mass spectrometry mercury-binding proteins
其他题名	高效液相色谱2同位素稀释2电感耦合等离子体质谱法研究大鼠体内的汞结合蛋白
通讯作者	Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China ; Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
英文摘要	Mercury-binding proteins in brain and liver cytosol of the dam and pup rats after methylmereury in utero, and lactation exposure were determined by high performance liquid chromatography ( HPLC)-inductively coupled plasma mass spectrometry(ICP-MS) hyphenated technique. The contents of mercury in the brain and liver cytosol of dam and pup rats were quantitatively calculated with the method of post-column isotope dilution (ID) ICP-MS. It was shown that there was a good coincidence between the methods of HPLC-ID-ICP-MS and direct ID-ICP-MS on total mercury concentration. The results demonstrated that HPLC-ID-ICP-MS could provide a reliably qualitative and quantitative results for mercury-binding protein study in organisms. Such a technique could also be useful for speciation study of other trace elements.
学科主题	Chemistry
类目[WOS]	Chemistry, Analytical
研究领域[WOS]	Chemistry
原文出处	SCI
语种	英语
WOS记录号	WOS:000247823600005
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/238521]
专题	高能物理研究所_院士高能物理研究所_实验物理中心高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Shi JW,Feng WY,Wang M,et al. Study on mercury-binding proteins in rats by hyphenated technique of high performance liquid chromatography-isotope dilution-inductively coupled plasma-mass Spectrometry[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2007,35(6):803-808.
APA	史俊稳.,丰伟悦.,王萌.,李柏.,汪冰.,...&Chai, ZF.(2007).Study on mercury-binding proteins in rats by hyphenated technique of high performance liquid chromatography-isotope dilution-inductively coupled plasma-mass Spectrometry.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,35(6),803-808.
MLA	史俊稳,et al."Study on mercury-binding proteins in rats by hyphenated technique of high performance liquid chromatography-isotope dilution-inductively coupled plasma-mass Spectrometry".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 35.6(2007):803-808.