Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers

	Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers
	Wang,Yupeng; Yan,Lesan; Li,Bin; Qi,Yanxin; Xie,Zhigang; Jing,Xiabin; Chen,Xuesi; Huang,Yubin
刊名	macromolecular bioscience
	2015
卷号	15 期号:9 页码:1304-1313
关键词	BLOCK-COPOLYMERS POLYMER MICELLES SOLID-SURFACES ADSORPTION NANOPARTICLES CHEMISTRY DENSITY DESIGN
通讯作者	huang,yb
英文摘要	the protein adsorption and self-assembly behavior of biocompatible graft copolymer, poly(lactide-co-diazidomethyl trimethylene carbonate)-g-poly(ethylene glycol) [p(la-co-dac)-g-peg], were systematically studied. the graft copolymers showed enhanced resistance to non-specific protein adsorption compared with their block copolymer counterparts, indicative of the increased effect of peg density beyond peg length. diverse nanostructures including vesicles can be assembled from the amphiphilic graft copolymers with well-defined nano-sizes. hemoglobin (hb), as a model protein, can be entrapped in the formed vesicles and keep the gas-binding capacity. the reduced release rate of hb from graft copolymer vesicles indicated the relatively stable membrane packing compared with block copolymer counterpart.
收录类别	SCI
语种	英语
公开日期	2016-05-31
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/67806]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Wang,Yupeng,Yan,Lesan,Li,Bin,et al. Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers[J]. macromolecular bioscience,2015,15(9):1304-1313.
APA	Wang,Yupeng.,Yan,Lesan.,Li,Bin.,Qi,Yanxin.,Xie,Zhigang.,...&Huang,Yubin.(2015).Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers.macromolecular bioscience,15(9),1304-1313.
MLA	Wang,Yupeng,et al."Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers".macromolecular bioscience 15.9(2015):1304-1313.