Enantioselective Cu-catalyzed decarboxylative propargylic amination of propargyl carbamates

	Enantioselective Cu-catalyzed decarboxylative propargylic amination of propargyl carbamates
	Zou, Yuan 1,2; Zhu, Fu-Lin 2; Duan, Zheng-Chao 3; Wang, Ya-Hui 2; Zhang, De-Yang 2; Cao, Zhong 1; Zheng, Zhuo 2; Hu, Xiang-Ping 2
刊名	tetrahedron letters
	2014-03-19
卷号	55 期号:12 页码:2033-2036
关键词	Copper Asymmetric catalysis Decarboxylation Propargylic amination Propargyl carbamate
通讯作者	胡向平
英文摘要	a copper-catalyzed asymmetric propargylic amination with a chiral ketimine p,n,n-ligand that proceeds via decarboxylation of propargyl carbamates has been developed. the reaction can be performed under the mild condition for a broad range of substrates, providing the corresponding propargylic amines in high yields and with up to 97% ee. this reaction represents a new and facile access to optically active propargylic amines. (c) 2014 elsevier ltd. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, organic
研究领域[WOS]	chemistry
关键词[WOS]	substitution-reactions ; carbonyl groups ; amines ; acetates ; esters ; ligands ; imines ; nucleophiles ; additions ; alkynes
收录类别	SCI ; IC ; CCR
语种	英语
WOS记录号	WOS:000334480700018
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/144319]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Changsha Univ Sci & Technol, Sch Chem & Biol Engn, Changsha 410004, Hunan, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 3.Hubei Univ Nationalities, Sch Chem & Environm Engn, Enshi 445000, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Zou, Yuan,Zhu, Fu-Lin,Duan, Zheng-Chao,et al. Enantioselective Cu-catalyzed decarboxylative propargylic amination of propargyl carbamates[J]. tetrahedron letters,2014,55(12):2033-2036.
APA	Zou, Yuan.,Zhu, Fu-Lin.,Duan, Zheng-Chao.,Wang, Ya-Hui.,Zhang, De-Yang.,...&Hu, Xiang-Ping.(2014).Enantioselective Cu-catalyzed decarboxylative propargylic amination of propargyl carbamates.tetrahedron letters,55(12),2033-2036.
MLA	Zou, Yuan,et al."Enantioselective Cu-catalyzed decarboxylative propargylic amination of propargyl carbamates".tetrahedron letters 55.12(2014):2033-2036.