Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies

	Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies
	Cui YY(崔岩岩); Wang YL(王雅兰); Zhao LN(赵丽娜); Cui, YY; Wang, YL; Zhao, LN
刊名	SMALL
	2015
卷号	11 期号:38 页码:5118-5125
通讯作者	王雅兰 ; 赵丽娜
英文摘要	The native cysteine (Cys)-Ag-3 cluster hydrogel is approved for the first time by both experimental and theoretical studies. From the detailed molecular structure and energy information, three factors are found to ensure the self-assembly of Cys and Ag-3, and result in the hydrogel. First, the Ag-S bonds make Cys and Ag-3 form Cys-Ag-3-Cys monomer. Second, intermolecular hydrogen bonds between carboxyl groups of adjacent monomer push them self-assembled. Third, more monomer precisely self-assemble to produce the -[Cys-Ag-3-Cys](n) multimer, e.g., a single molecular chain with the left-handed helix conformation, via a benign thermodynamic process. These multimers entangle together to form micro-network to trap water and produce hydorgel in situ. The hydrogen bonds of hydrogel are sensitive to thermal and proton stimuli, and the hydrogel presents lysosome targeting properties via fluorescent imaging with biocompatibility.
学科主题	Chemistry; Science & Technology - Other Topics; Materials Science; Physics
类目[WOS]	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
收录类别	SCI ; EI ; CA
WOS记录号	WOS:000362819700015
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/228768]
专题	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Cui YY,Wang YL,Zhao LN,et al. Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies[J]. SMALL,2015,11(38):5118-5125.
APA	崔岩岩,王雅兰,赵丽娜,Cui, YY,Wang, YL,&Zhao, LN.(2015).Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies.SMALL,11(38),5118-5125.
MLA	崔岩岩,et al."Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies".SMALL 11.38(2015):5118-5125.