Determination of estrogens and estrogenic activities in water from three rivers in Tianjin, China

	Determination of estrogens and estrogenic activities in water from three rivers in Tianjin, China
	Rao, KF; Lei, BL; 李娜(多); Li, N; Ma, M; Wang, ZJ
刊名	JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA
	2013
卷号	25 期号:6 页码:1164-1171
关键词	river water endocrine disrupting compounds (EDCs) yeast assay bioassay
英文摘要	Studies on estrogenic disrupting compounds (EDCs) occurrence and identification of main responsible compounds in river water discharged into the sea are of significance. In the present research, we screened estrogenic activities of 10 river water samples from 3 main rivers discharged into Bohai Sea in Tianjin using a recombinant two-hybrid yeast assay and chemical analysis by gas chromatography-mass spectrometry. All sample extracts induced significant estrogenic activity, with 17 beta-estradiol equivalents (EEQ) of raw water ranging from 5.72 to 59.06 ng/L. Six most concerned EDCs in the river water samples including estrone, 17 beta-estradiol, 17 alpha-ethinylestradiol, estriol, diethylstilbestrol and estradiol valerate were determined, with their concentrations up to 50.70, 31.40, 24.40, 37.20, 2.56, and 8.47 ng/L, respectively. Through causality analysis by comparing the EEQ values of yeast assay and chemical analysis, 17 alpha-ethinylestradiol and 17 beta-estradiol were identified as the main contributors to the estrogenic effects of the river samples, accounting for the whole estrogenic activities (62.99% to 185.66%), and estrogen antagonistic compounds might presented in the heavy polluted water samples. The proposed approach using both chemical analysis and bioassay could be used for identification and evaluation of the estrogenic activity of EDCs in river water.
学科主题	Environmental Sciences & Ecology
收录类别	SCI
WOS记录号	WOS:000320749900015
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/224113]
专题	高能物理研究所_多学科研究中心
推荐引用方式 GB/T 7714	Rao, KF,Lei, BL,Li N,et al. Determination of estrogens and estrogenic activities in water from three rivers in Tianjin, China[J]. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA,2013,25(6):1164-1171.
APA	Rao, KF,Lei, BL,李娜,Li, N,Ma, M,&Wang, ZJ.(2013).Determination of estrogens and estrogenic activities in water from three rivers in Tianjin, China.JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA,25(6),1164-1171.
MLA	Rao, KF,et al."Determination of estrogens and estrogenic activities in water from three rivers in Tianjin, China".JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA 25.6(2013):1164-1171.