Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 固体润滑国家重点实验室

	Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy
	Lin, Bingpeng 1; Zhong, Mei 1; Zheng, Chengdong 1; Cao, Lin 1; Wang, Dengli 1; Wang, Lina 1; Liang J(梁军)2 ; Cao, Baocheng 1
刊名	Surface and Coatings Technology
	2015
卷号	281 页码:82-88
关键词	Biomimetic coating Polydopamine Corrosion resistance Magnesium alloy Cytotoxicity Hydroxyapatite
ISSN号	0257-8972
通讯作者	Cao, Baocheng
英文摘要	Mg alloys have great potential in biodegradable orthopedic implant applications owing to their rapid degradation in physiological environments and mechanical properties similar to those of bone. However, the extremely high corrosion rate of magnesium alloys has also restricted their medical applications. In this work, a hydroxyapatite (HA) coating was prepared by polydopamine (PDA) induced biomimetic mineralization in a CaP solution to improve the in vitro corrosion resistance and biocompatibility of the AZ31 Mg alloy. The evolution of the phase structure, chemical composition, and surface morphology of the modified AZ31 Mg alloy substrate was evaluated by scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy. Potentiodynamic polarization and hydrogen evolution tests demonstrated that the corrosion resistance of the modified AZ31 Mg alloy significantly increased compared with that of the pristine sample. Cytotoxicity testing and cell morphology analysis showed that the as-modified alloy did not induce toxic effects, and promoted the proliferation of L-929 cells. The results suggest that the dopamine-induced biomimetic apatite coating approach is of significant value in the development of biodegradable Mg alloy implants.
学科主题	材料科学与物理化学
收录类别	SCI
资助信息	the Natural Science Foundation of Gansu Province, China (grant no. 1208RJZA236)
语种	英语
WOS记录号	WOS:000366072200011
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/19149]
专题	兰州化学物理研究所_固体润滑国家重点实验室
作者单位	1.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Lin, Bingpeng,Zhong, Mei,Zheng, Chengdong,et al. Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy[J]. Surface and Coatings Technology,2015,281:82-88.
APA	Lin, Bingpeng.,Zhong, Mei.,Zheng, Chengdong.,Cao, Lin.,Wang, Dengli.,...&Cao, Baocheng.(2015).Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy.Surface and Coatings Technology,281,82-88.
MLA	Lin, Bingpeng,et al."Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy".Surface and Coatings Technology 281(2015):82-88.