Alkaloids with Different Carbon Units from Myrioneuron faberi | |
Cao,Ming-Ming; Zhang,Yu; Huang,Sheng-Dian; Di,Ying-Tong; Peng,Zong-Gen; Jiang,Jian-Dong; Yuan,Chun-Mao; Chen,Duo-Zhi; Li,Shun-Lin; He,Hong-Ping | |
刊名 | JOURNAL OF NATURAL PRODUCTS |
2015-11-01 | |
卷号 | 78期号:11页码:2609-2616 |
英文摘要 | Three new Myrioneuron alkaloids, myrifamines A-C (1-3), with unique skeletons were isolated from Myrioneuron faberi. The absolute configuration of 1 was confirmed by single-crystal X-ray diffraction analysis, and the stereochemistry of the other two alkaloids was determined using a combination of ROESY experiments and calculated and experimental electronic circular dichroism spectra. Myrifamine C (3) is the first example of a symmetric dimer among the Myrioneuron alkaloids. Known alkaloids myrionamide (4) and schoberine (5) were also isolated, and experimental NMR and X-ray diffraction data suggest their structural revision. Compound 2 showed significant inhibitory activity toward the hepatitis C virus in vitro, with a therapeutic index (CC50/EC50) greater than 108.7. |
类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
关键词[WOS] | NUTANS |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000366005800013 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/25266] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
推荐引用方式 GB/T 7714 | Cao,Ming-Ming,Zhang,Yu,Huang,Sheng-Dian,et al. Alkaloids with Different Carbon Units from Myrioneuron faberi[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(11):2609-2616. |
APA | Cao,Ming-Ming.,Zhang,Yu.,Huang,Sheng-Dian.,Di,Ying-Tong.,Peng,Zong-Gen.,...&Hao,Xiao-Jiang.(2015).Alkaloids with Different Carbon Units from Myrioneuron faberi.JOURNAL OF NATURAL PRODUCTS,78(11),2609-2616. |
MLA | Cao,Ming-Ming,et al."Alkaloids with Different Carbon Units from Myrioneuron faberi".JOURNAL OF NATURAL PRODUCTS 78.11(2015):2609-2616. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论