A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa
Jiang HL(姜海龙)1,2,4; Wang R(王瑞)1,2; Li, Jian-Yong3; Shi YP(师彦平)1,2
刊名Natural Product Research
2015
卷号29期号:20页码:1878-1883
关键词cytotoxicity daphnane diterpenoid Daphne genkwa
ISSN号1478-6419
通讯作者师彦平
英文摘要

The phytochemical investigation of the flower buds of Daphne genkwa yielded eight highly oxygenated daphnane-type diterpene esters, including a new one, genkwanine N 20-palmitate (1) and seven known ones (2-8). The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with literature data. Furthermore, compound 1 showed potential cytotoxic activity in vitro, against A549 and Hep G2 tumour cell lines.

学科主题分析化学与药物化学
收录类别SCI
资助信息National Natural Science Foundation of China (grant number 81303202);(grant number 21375136);the open fund of the New Animal Drug Project of Gansu Province and the Key Laboratory of Veterinary Pharmaceutical Development of the Ministry of Agriculture (grant number 1610322011011)
语种英语
WOS记录号WOS:000360458200001
内容类型期刊论文
源URL[http://210.77.64.217/handle/362003/18579]  
专题兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
作者单位1.Chinese Acad Sci, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou 730000, Peoples R China
2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China
3.Lanzhou Inst Husb & Pharmaceut Sci CAAS, Key Lab New Anim Drug Project, Gansu Prov & Key Lab Vet Pharmaceut Dev, Minist Agr, Lanzhou 730050, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Jiang HL,Wang R,Li, Jian-Yong,et al. A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa[J]. Natural Product Research,2015,29(20):1878-1883.
APA Jiang HL,Wang R,Li, Jian-Yong,&Shi YP.(2015).A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa.Natural Product Research,29(20),1878-1883.
MLA Jiang HL,et al."A new highly oxygenated daphnane diterpene esters from the flower buds of Daphne genkwa".Natural Product Research 29.20(2015):1878-1883.
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